Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
The Genome Engineering and IPSC Center (GEiC) was formed by the consolidation of two pre-existing cores, the Genome Engineering Center and the Induced Pluripotent Stem cell (iPSC) core, both established by the Department of Genetics in the past few years. These two Centers were established to facilitate the use of sophisticated genome editing of cells and organisms. The recent merging of these Centers reflects the new opportunities afforded by uniting these powerful new technologies. The GEiC includes a consultative service whereby investigators are able to query skilled personnel adept in genomic engineering technologies and the generation and differentiation of patient-derived induced pluripotent stem cells (iPSCs). Genome engineering uses custom endonucleases to create targeted DNA double-strand breaks in genomic DNA. The repair of these DNA breaks by the endogenous cellular repair machinery can lead to targeted, user-defined genomic modifications. These modifications can be anything from a targeted gene knockout to the precise change of a single nucleotide to gene fusions with epitope tags or fluorescent reporters.
Candidates with extensive prior experience in cell, molecular biology or related fields with at least a Bachelor’s degree are encouraged to apply.
Mammalian cell culture- iPSC or hESC culturing is preferred
Basic microbiology skills
Proficiency in basic molecular biology techniques including DNA and RNA isolation and purification; PCR, reverse transcription PCR, cloning, restriction digests, and sequence analysis
Experience with flow cytometry is a plus
Working knowledge of genome editing using CRISPR/Cas9, TALENs, or ZFNs a plus
Working knowledge of Microsoft Office and Image J is a plus
Demonstrated ability to work independently and communicate effectively.
Should have troubleshooting skills, an ability to maintain complete and organized records, and a working knowledge of computer software and general lab equipment.
Productivity and the ability to get a large number of projects completed in an efficient manner is highly preferred.
Applicant Special Instructions:
Works in laboratory environment with potential exposure to biological, chemical and radioactive hazards. Must be physically able to wear protective equipment.
Department Name/Job Location:
This opportunity is in the Department of Genetics – Genome Engineering and iPSC Center located in the Biotech Building on the Medical School Campus.
This opportunity is full-time and works approximately 40 hours per week. Hours are generally normal business hours but may vary due to the timing for experiments and other research activity deadlines.
The hiring range for this position is commensurate with experience.
This opportunity is eligible for full-time benefits. Please visit our website at http://hr.wustl.edu to view a summary of benefits.
Internal Applicant Instruction:
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplin...ary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.