The overall goal of The Stanley Neurovirology Laboratory of the Johns Hopkins University School of Medicine is to develop a training and research program devoted to understanding the role of infection and immunity in the etiology of schizophrenia and bipolar disorder. The candidate will develop, conduct and evaluate scientific research in this laboratory environment. This laboratory position requires experience in and an advanced understanding of microbiology, molecular biology and protein biochemistry. The applicant must have strong technical, analytic and organizational skills, as well as a good working knowledge of applying the scientific method investigative process to the goals of our division. Attention to detail and the ability to learn new technical and analytical skills is required. Specifically, this position requires the execution and trouble-shooting of RNAand DNA-based procedures and immunological techniques including ELISAs, Western blotting, immunoprecipitations and immunohistochemistry using both clinical samples and experimental rodent models. A general understanding of standard laboratory equipment including automated systems, real-time and end-point PCR thermocyclers, sample quantification devices, immunoblotting apparatus, digital imager and light microscopes is recommended. The range of duties includes, but is not limited to: project planning, experimental design, developing methodology, conducting procedures, modifying procedures as needed, data collection and analysis, laboratory management, project management, preparing reports, and communication and instruction. Work may include the training and supervision of staff, students and others in performing specific techniques or phases of experiments.
Specific Duties and Responsibilities:
Develops experimental designs and has primary responsibility for planning, implementation, evaluation and interpretation of results in collaboration with the PI.
Suggests, performs, and evaluates immune- and neural-related biomarker and other measures in human and experimental rodent samples through application of DNA-, RNA- and protein-based procedures.
Organizes projects by maintaining up-to-date databases of records of daily experiments, laboratory protocols, biospecimen inventories, reagent inventories and project-specific budgets.
Identifies problems, troubleshoots and analyzes variation observed and reported in regular testing protocols; modified, refines or adapts techniques and procedures; modifies and/or adjusts quality control measures.
Coordinates and/or conducts multiple, concurrent assignments or a multi-faceted project.
Compiles, analyzes, and interprets research data using various computer software applications.
Monitors documentation of results; reviews and recognizes documentation, which may lead to modification and adaptation of research methodologies; may collaborate with others. Adapts and/or modifies experimental methods based upon interpretation of data.
Conducts library research and participates in editing and preparing manuscripts, scientific illustrations and computer graphics for publications.
Oversees and assures laboratory compliance with regulatory requirements and JHU standards, policies and procedures.
Works with research staff to prioritize and schedule projects.