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Application Review Date
The First Review Date for this job is: January, 6, 2017
The teaching and research activities of the Department of Molecular and Cell Biology (MCB) concern the molecular structures and processes of cellular life and their roles in the function, reproduction, and development of living organisms.
This agenda covers a broad range of specialized disciplines, including biochemistry, biophysics, molecular biology, structural biology, genetics, genomics, bioinformatics, cell biology, developmental biology, tumor biology, microbiology, immunology, pathogenesis and neurobiology.
The types of living organisms from which the departmental faculty draws its working materials are as diverse as its disciplinary specializations, ranging from viruses and microbes through plants, roundworms, annelids, arthropods, and mollusks to fish, amphibia, and mammals.
The faculty of the department is organized into five divisions: Biochemistry and Molecular Biology; Cell and Developmental Biology; Genetics, Genomics and Development; Neurobiology; and Immunology and Pathogenesis.
The job is for an individual with experience in standard molecular biology techniques and the ability and desire to help manage an academic research lab at UC Berkeley. The candidate's responsibilities will be limited to the Kramer lab.
Molecular Biology: Subcloning and site-directed mutagenesis of genes important for nervous system function, including primer design, plasmid preps, restriction digests, gel electrophoresis, ligation, sequencing and CRISPR/Cas 9 -mediated gene editing. Protein biochemistry techniques including immunopurification, immunolabeling, and Western blotting will also be employed. The employee should be well-versed in PCR, gel electrophoresis apparatus for DNA and protein analysis, computer programs for sequencing and homology searching, and database computer programs for archiving plasmid DNAs.
The employee will be using the above molecular biology techniques as a step in generating transgenic zebrafish and mice. He/she will help train other personnel (a lab tech and a grad student) who will be maintaining the fish and mouse colonies and carrying out behavioral experiments. The employee will be given considerable independence in designing DNA constructs, and thus will make a significant contribution to the overall research mission of the lab. This may merit authorship on scientific papers.
Lab Manager Duties: Mentoring, training, and supervising of Staff Research Associate I, who will be maintaining the zebrafish and mouse colony (including breeding) and carrying our behavioral light-response experiments. Supervising animal use and biosafety compliance. This includes preparing and appending the Master Animal Use Protocol and Protocols for EH&S.
Laboratory organization: This includes scheduling lab meetings, maintaining general lab organization, including purchasing supplies, and maintaining the chemical inventory. The employee will also train lab technicians and undergraduate students who will perform daily technical support tasks.
Hands-on experience in molecular biology is essential including relevant experience with protein biochemistry.
Experience with molecular genetic manipulation (preferably in mice).
Strong professional communication and organizational skills and the ability to maintain lab supplies and supervise others. Education/Training:
Bachelor's in Biochemistry, Molecular Biology, Neuroscience, or related discipline or equivalent experience, plus 2 years working experience in a biomedical research lab.
Training in EH&S protocols, Chemical Safety, and Animal Care and Use. Preferred Qualifications
Knowledge of and interest in molecular neurobiology.
Salary & Benefits
For information on the comprehensive benefits package offered by the University visit:
The University of California was chartered in 1868 and its flagship campus - envisioned as a "City of Learning" - was established at Berkeley, on San Francisco Bay. Today the world's premier public university and a wellspring of innovation, UC Berkeley occupies a 1,232 acre campus with a sylvan 178-acre central core. From this home its academic community makes key contributions to the economic and social well-being of the Bay Area, California, and the nation.