| Position Summary: Conducts research to study RNA polymerase. Uses biochemistry, genetics, high-throughput sequencing and molecular biology to conduct research on the use of metabolic effectors as non-canonical initiating nucleotides (NCINs) for transcription initiation by RNA polymerase. Prepares text, tables, and figures for patent applications publications. Presents results at scientific meetings. Performs professional level experiments and research using various techniques. Carries out routine and non-routine work with review of work outputs by supervisor. Documents work performed and maintains a notebook and database. Communicates effectively with supervisor. Uses and helps maintain highly specialized equipment, in addition to maintaining and keeping the workplace and laboratory organized in a clean and safe manner in accordance with established procedures. Trains and leads research associates, postdoctoral associates, students, and technicians in laboratory related activities. Performs professional work requiring specialized knowledge and application and use of concepts, theories, terminology, and practices. Minimum Education and Experience: Requires a doctorate in microbiology, biochemistry or an allied field and at least five years relevant postdoctoral experience. Requires in-depth understanding and hands-on experience in use of biochemistry, genetics, high-throughput sequencing and molecular biology to study transcription. Requires in-depth understanding and hands-on experience in molecular cloning, sequencing, and site-directed mutatgenesis. Required Knowledge, Skills, and Abilities: Experience in structural and functional analysis of RNA polymerase is preferred. Effective spoken and written English required. Experience in chromatography (including FPLC and preferably including HPLC) and electrophoresis required. Experience in work with chemical hazards, cryological hazards, and radiological hazards required. Experience in work with biological hazards (biosafety levels 1 and 2) preferred. Physical Demands and Work Environment: Average to above-average levels of mobility expected for laboratory environment., Average to above-average levels of upper-body strength expected for for lifting and working with bioreactors, large-volume culture flasks, Dewar flasks, cryo reservoirs, and other heavy items.. Posting Number: 18FA0233 Location: Busch (RU-New Brunswick) | 
