Conducts experimental research lab work and/or assists in design of one or more specific phase(s) of entire project(s). May complete mathematical calculations, and/or computer tasks and/or assist in judging validity of data. Follows appropriate protocols, policies, procedures, regulations, Good Clinical and Good Laboratory Practices.
More specifically, the individual will be joining the Backman Lab in the Biomedical Engineering Department, a research group that focuses on cutting edge research to cure disease. The group is comprised of a 23 person team. And will be responsible for preparing samples using a variety of methods including chemical fixation, osmication, room temperature resin-embedding, and ultramicrotomy for Electron Microscopy (EM). The successful candidate will also collect data using a transmission electron microscope and a scanning transmission electron microscope, including tilt series collection. The Research Technologist will also perform tomography reconstruction and maintain sample logs.
The Research Technologist will be working in collaboration with graduate students, postdocs, and research associates in the lab for electron microscopy related experiments such as testing new sample preparation protocols.
The laboratory skills and training include expertise in electron microscopy imaging, tomography collection and reconstruction, sample preparation, and ultramicrotomy.
This is a one year termed position subject to renewal dependent on performance and available funding.
Following protocols, designs, sets-up and conducts basic experiments. Analyzes and troubleshoots protocols and data obtained from individual experiments and recommends alternatives and suggestions to improve processes, validity and/or accuracy.
Analyzes and troubleshoots protocols and data obtained from individual experiments and recommends alternatives and suggestions to improve processes, validity and/or accuracy.
A fully functioning level of understanding in the following highlighted skills is required:
Other (please specify):
Electron Microscopy imaging:
Cell/tissue fixation/processing for EM, embedding, preparation of resin blocks, ultramicrotomy
Maintains detailed records of results which may include collecting, extracting and entering data;
Preparing charts and graphs for presentations and publications.
Perform scientific literature searches in support of research;
Completes portions of grant applications, manuscripts and publications.
May track and summarize lab supply expenses
Verify accuracy of invoices.
Order and/or maintain inventory of reagent, mice and/or lab supplies.
Completes other duties as assigned
Performs other duties as assigned.
Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience.
Minimum Competencies: (Skills, knowledge, and abilities.)
Demonstrated laboratory experience;
Demonstrated ability to follow detailed instructions as required by research protocols;
Demonstrated computer skills, including spreadsheets and basic computations;
Attention to detail and accurate record keeping;
Ability to work independently and in a team environment;
Expertise in performing transmission electron microscopy imaging for biological and soft materials;
Experience in wet-lab experiments, including sample preparation for electron microscopy and/or fluorescence microscopy;
Knowledge in a technical field (e.g. biology, biochemistry, microbiology, optical, biomedical, chemical engineering, physics, chemistry) or the equivalent combination of education, training, and experience from which comparable skills can be acquired;
Extremely good interpersonal skills;
Excellent organizational skills;
Good analytical skills;
Basic computer skills and experience with Python, MS Office;
A master's degree in electron microscopy, materials science or related field. Or the equivalent combination of education, training, and experience from which comparable skills can be acquired.
One-year experience of electron microscopy sample preparation for biology, electron microscope imaging, and/or tomography collection and reconstruction.
Preferred Competencies: (Skills, knowledge, and abilities)
Be able to perform ultramicrotomy on resin-embedded samples;
Be able to perform electron tomography using transmission electron microscopy, scanning transmission electron microscopy;
Computer skills include experience with tomography reconstruction packages such as IMOD, TomoPy, TxBR, etc.
Be able to perform sample preparation with different techniques besides room temperature resin-embedding, such as critical point drying, plunge freezing, high-pressure-freezing, and freeze-substitution;
Demonstrates excellent attention to detail, can work quickly and accurately, organizing tasks and delivering quality with efficiency;
Ability to work and maintain strong relationships with department managers, members of your team and other departmental staff;
Capacity to work under pressure and comply with deadlines.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 38832
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.