Postdoctoral Scholar - Infectious Disease and Vaccinology - School of Public Health
Position: Postdoctoral Scholar - Employee Location: University of California, Berkeley, CA Salary: Commensurate with experience Target Start Date: October 2020
The School of Public Health at the University of California, Berkeley seeks application for a Postdoctoral Scholar, in the area of Infectious Disease and Vaccinology. This is a full-time position with an expected start date in Fall 2020
The Harris lab takes a multidisciplinary approach to study virology, pathogenesis, immunology, clinical aspects, epidemiology, and control of dengue, Zika, and chikungunya, the most prevalent arboviral diseases in humans. The work addresses viral and host factors that modulate disease severity and investigates immune correlates of protection and pathogenesis using in vitro approaches, animal models, and research involving human populations.
Responsibilities: The candidate will investigate the B cell and antibody response, dynamics, and repertoire in natural human dengue (DENV) and Zika virus (ZIKV) infections as part of a long-term longitudinal pediatric cohort and hospital-based studies of dengue and Zika in Nicaragua. For example, we have observed asymmetries in protection and enhancement based on the sequence of infection with different DENV serotypes and ZIKV and we seek to explain these phenomena by analyzing the B cell and antibody repertoire in samples collected after different infection sequences as well as in relation to the virion structure of the subsequent infecting virus. Further, analysis of long-term antibody dynamics post-DENV and ZIKV infection has revealed different patterns of persistence versus decay, and we aim to define the antibody, B cell, and Tfh cell characteristics that determine the longevity of distinct antibody classes post-primary and post-secondary infection. The position may also involve assessment of the protective capacity of human monoclonal antibodies in murine models of DENV and ZIKV infection and disease. Overall, these studies involve collaborative investigations in the context of a Program Project on mechanisms of protective (and potentially pathogenic) flavivirus immunity in human populations.
Basic qualifications (at the time of application):
Ph.D. (or equivalent international degree), or enrolled in a Ph.D. (or equivalent international degree) granting program at the time of application
Additional qualifications (required by start date):
Ph.D.(or equivalent international degree)
Ph.D. in one of a variety of fields, including but not limited to Immunology, Virology and/or Microbiology
Experience in adaptive immune response and methods such as flow cytometry/FACS, ELISpot, etc.
Demonstrated substantial laboratory experience in human and/or murine immunology
Letters of reference may be solicited for finalists. We will seek your permission before contacting your references. All letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality (https://apo.berkeley.edu/ucb-confidentiality-policy) prior to submitting their letters.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action, policy see http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct.
UC Postdocs are exclusively represented by the International Union, United Automobile, Aerospace, and Agricultural Implement Workers of America (UAW) local (5810).
Diversity, equity, and inclusion are core values at UC Berkeley and The School of Public Health. Our excellence can only be fully realized by faculty, students, and staff who share our commitment to these values. Successful candidates for our academic positions will demonstrate evidence of a commitment to advancing equity and inclusion.
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