The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement, artistic pursuits, and natural beauty.
At the University of Washington, diversity is integral to excellence. We value and honor diverse experiences and perspectives, strive to create welcoming and respectful learning environments, and promote access, opportunity and justice for all.
UW Microbiology has an excellent opportunity for a Full-Time, Temporary Research Scientist 3 to perform critical research related to COVID-19.
The position is anticipated to be 9 months in duration. The position supports a research project that will be focused on the discovery of nanobody therapeutics against COVID-19 as well as vaccine development for COVID-19 and influenza. Specifically, this position will utilize next generation sequencing to characterize the antibody repertoire in alpacas immunized with SARS-CoV-2 antigens, as well as the cloning of next generation vaccine candidates in RNA and DNA vaccine platforms.
Primary Research Responsibilities (50%)
•Prepare illumina sequencing libraries from RNA extracted from peripheral blood mononuclear cells isolated from alpacas that have received multiple immunizations with a SARS-CoV-2 vaccine antigen. •Assist with bioinformatic analysis of sequencing data. •Clone novel immunogens or therapeutic protein genes into RNA/DNA vaccine platform. •Design and conduct experiments investigating immunogenicity and efficacy of RNA and DNA vaccines as well as therapeutics in mouse models of SARS-CoV-2 and influenza virus infection.
Data Analysis and Scientific Manuscript Preparation (25%)
•Data analysis, presentation of results, writing reports, coordinating efforts and communications with other researchers in the lab.
Additional Laboratory Responsibilities (25%)
•Support PI in the preparation of grant applications including preliminary results and developing experimental approach (10%). •Supervise and train entry-level research assistants and undergraduate researchers (10%). •Additional lab management duties include ordering, supply budget monitoring, scheduling research activities and biweekly lab meetings and coordination of lab equipment maintenance (5%).
•Bachelor's degree in biology or related field. •Three to five years of job-related laboratory research experience. •Proficiency in sequencing library preparation and other molecular biology techniques including cloning. •Some experience or interest in evaluating therapeutics and vaccines in small animal models. •Excellent communication skills and ability to maintain accurate detailed records. •Proficiency with Microsoft Excel, Word and Powerpoint. •Ability to work independently, troubleshooting potential bottlenecks, and managing the work flow of multiple projects and conflicting deadlines.
•Experience with animal handling, injections, and ELISAs. •Prior use of Prism software. •Experience with general lab maintenance. •Prior experience supervising technicians or student researchers.
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter, and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.