The Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University is looking for a talented postdoctoral scholar in the laboratory of Akshaya K. Meher. The scholar will participate in the laboratory's mission to understand the interaction of immune cells and develop immunotherapeutics. For more information, please visit the Meher lab at https://microbiology-immunology.ecu.edu/mehera19/. Primarily, the scholar is responsible for independent and collaborative development, implementation, and analysis of scientific research involving the roles of B lymphocytes and innate immune cells in murine models of aortic aneurysms and diabetes.
Responsibilities include management of all aspects of the project involving gene cloning, protein expression in E. coli and eukaryotic cell lines, protein purification using an in-house ÄKTA protein purification system, mouse breeding, minor murine surgery, phenotyping murine immune cells using multicolor flow cytometry, isolation and culture of primary immune cells, Western blotting, intracellular signaling, real-time RT-PCR, immunohistology, confocal microscopy, live cell metabolic assays using an in-house Seahorse XFe24 Analyzer, metabolomics, RNA sequencing data analysis, and IPA. The scholar is expected to perform hypothesis-driven research and assist PI in submitting extramural grant applications and manuscripts.
Duties include: hypothesis development, literature review, perform experiments, collection of primary and reproducible data, detail record keeping, scientific writing, supervising of undergraduate research students and graduate research students, overseeing data collection procedures, supervising experimental procedures, review of data for quality control, supervision of data entry/data analysis, use of descriptive and multivariate statistics, and the development of independent and collaborative presentations and publications. Scholars are expected to demonstrate compliance with established guidelines and regulatory standards for research including biosafety and chemical safety, responsible conduct of research and human subjects training. Approximately 95% of the postdoctoral scholar's time will be devoted to research. Approximately 5% of the postdoctoral scholar's time will be devoted to managing the day-to-day activity of undergraduate and graduate research students in the laboratory.
Special Instructions To Application:
To be considered for this position, all applicants must apply through PeopleAdmin and attach their CV or resume, cover letter and names and contact information of 3 references. Appointments are typically for a one-year period. Five years (typically five appointments of one year) is typically the maximum total period that any individual may serve as a Scholar. The University, in its sole discretion has the option to renew or extend any appointment, subject to the availability of funds, past performance evaluations and/or any other lawful reasons. For other information on the ECU Office of Postdoctoral Affairs, please visit our website at: https://rede.ecu.edu/postdoctoral/
The candidate should hold a PhD in biochemistry, immunology, pharmacology, molecular biology, or a closely related field. Proficiency in standard molecular biology, real-time RT-PCR, protein expression, flow cytometry, ELISA, Western blotting, mouse handing techniques, and minor surgery are required. Proficiency in hypothesis-driven experimental design, data analysis, and record keeping are required. Interested candidates must be capable of working independently and have demonstrated excellence in both written and oral communication skills. English proficiency is required.
Full time or Part time: Full Time
Position Location (city): Greenville
Position Number: PDS-MCBI-08-20
Organizational Unit Overview:
The Department of Microbiology and Immunology is a distinguished research and teaching facility of East Carolina University School of Medicine consisting of approximately 50 people. This department provides an academic base for teacher-scientists employed by the School of Medicine at East Carolina University in the disciplines of microbiology, immunology, molecular biology and other related disciplines. The department provides instruction to medical students, dental students, and graduate students. The department also provides guidance and research experience to graduate students seeking advanced degrees in microbiology and immunology. The department also offers a postdoctoral research training program. The department supports an array of faculty (16)-directed research programs of which many are supported by extramural grants and/or contracts. The department provides service to the school, university, state, nation, and to the profession by activities of faculty members on committees, study sections, in professional organizations, as consultants, and through other activities.
To be a national model for student success, public service and regional transformation, East Carolina University uses innovative learning strategies and delivery methods to maximize access; prepares students with the knowledge, skills and values to succeed in a global, multicultural society; develops tomorrow's leaders to serve and inspire positive change; discovers new knowledge and innovations to support a thriving future for eastern North Carolina and beyond; transforms health care, promotes wellness, and reduces health disparities; and improves qualify of life through cultural enrichment, academics, the arts, and athletics. We accomplish our mission through education, research, creative activities, and service while being good stewards of the resources entrusted to us. East Carolina University delivers on the promise of opportunity. We open doors. We improve lives. We transform the present, and we discover the future. In these ways and more, we serve our community, our state, our nation and our world as together we reach toward our greatest potential. Tomorrow starts here.