THIS IS A TIMELIMITEDPOSITIONWITH AN ESTIMATEDDURATION OF 1-3 YEARS.
The objective of this position is to serve as a Research Specialist in Dr. Rita Tamayo's lab. Her laboratory investigates mechanisms of pathogenesis of the bacterium Clostridioides difficile. This work involves genetic manipulation of putative virulence genes for analysis of function and regulation, biochemical analysis of macromolecular interactions (e.g., DNA-protein and RNA-protein interactions), and in vitro and in vivo models of disease. In vitro models include a co-culture system to examine the interaction between C. difficile, intestinal microbiota, and human epithelial cells. In vivo models include rodent models of C. difficile colonization and pathogenesis.
The purpose of this position is to assist and support the principal investigator (PI) in managing the laboratory and performing essential scientific experiments. Lab management duties include ordering supplies, coordinating with core facilities and collaborators, organizing and maintaining reagent spreadsheets, and training new lab personnel. Scientific experiments and assays include: Molecular biology (RNA/DNA extractions, PCR and qPCR, microbiome sequencing), microbial culturing, and immunological assays; Genetic manipulation of bacteria; Tissue culture and co-culture with bacterial strains; Mouse and hamster models of C. difficile disease (animal handling, fecal collection, necropsy, downstream assays)
Education and Experience:
Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
Previous experience working in a research lab setting. Our projects relate to immunology and microbiology of C. difficile infection, so our candidate must be willing to work with pathogenic bacteria (mostly C. difficile), intestine and stool samples, and mouse and hamster models of C. difficile disease. In this position, the candidate will need to be adept at many different types of laboratory work. The candidate must be organized, reliable, scientifically motivated, with keen attention to detail and the ability to work as part of a research team.
The preferred candidate will have:
Bachelor's degree in Biology, Microbiology, Immunology, Chemistry, or similar discipline.
3+ years part-time experience or 1+ year full time hands-on relevant laboratory experience.
Demonstrated experience in Molecular Biology including primer design, PCR, and DNA cloning.
Excellent computer skills (esp. Microsoft Office Word, Excel, and PowerPoint)
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.