This position will remain open until a successful candidate has been identified.
UCSD Layoff from Career Appointment: Apply by 8/5/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 8/16/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.
Faculty members of the Division of Female Pelvic Medicine and Reconstructive Surgery in the Department of Obstetrics, Gynecology, and Reproductive Sciences treat women with pelvic floor disorders such as pelvic organ prolapse, and urinary and fecal incontinence. The Alperin laboratory (https://alperinlab.org/) is focused on understanding the pathophysiology of these conditions. Specifically, we investigate the impact of pregnancy, maternal birth injury, and aging on the structure, function, and regenerative potential of pelvic skeletal muscles and how pathological alterations in these muscles contribute to the development of pelvic floor disorders. In addition, we explore the role of novel biomaterials in pelvic skeletal muscle regeneration.
Under supervision, incumbent will perform structural, histological, molecular, cellular, and functional analyses of human and animal tissue, as well as in vivo animal experiments. Secondly, incumbent will be responsible for the organization and presentation of the collected experimental data. Additional duties include laboratory management, instructing trainees in the laboratory on basic activities related to tissue dissection and preparation for microscopic, biochemical, cellular, and mechanical examination or testing. Responsibilities also involve preparation and maintenance of various biological media for research activities; operation and maintenance of laboratory equipment; ensuring laboratory safety, maintaining laboratory inventory; and collection and transportation of biological tissues.
Theoretical knowledge as required in a Bachelor's degree in biology/life sciences or a combination of education and experience.
Hands-on experience with in vivo animal experiments and handling of laboratory animals and human tissue. This includes euthanizing of animals and post-operative care.
Willingness to perform experiments involving the handling, dissection, and sacrifice of laboratory mice/rats. Willingness and ability to work with radioactive isotopes, recombinant DNA, biohazardous, radioactive materials, and toxic chemicals.
Hands-on experience with molecular biology experimental techniques, including but not limited to Western blots, qPCR, cell culture, and gel electrophoresis.
Knowledge of laboratory safety including biohazard handling and disposal techniques, and ability to ensure laboratory compliance with required safety regulations.
Ability to work with human tissue and transport biological tissue. Willingness to travel to the hospitals to collect and transport human tissue samples, collected from the research subjects in the operating room.
Good computer skills and experience with various software packages including graphing, drawing programs, and Excel.
Good verbal and written communication.
Ability to take initiative and handle responsibility.
Good interpersonal skills to be effective in communicating and interacting with a variety of people within a large laboratory setting and in administrative components within and outside the University.
Experience working with a variety of laboratory equipment, including but not limited to centrifuges, autoclaves, cryostat, microscopes.
Good organizational skills; ability to maintain a clean laboratory, tissue and supply inventory; ability to place/manage purchasing orders
Ability to inject and collect tissues from mice and rats.
Hands-on experience with preparation of solutions/media, and immunohistochemistry techniques.
Knowledge of rodent anatomy and reproductive functions.
Experience working with cell cultures.
Experience working with epifluorescent and confocal microscopes.
Employment is subject to a criminal background check.
Must be willing to work with human tissue and transport biological tissue.
Must be willing to work with biohazardous and radioactive materials.
Must be willing to work evenings and/or weekends as needed to accommodate experiments.
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.