ABOUT THE JOB This is a research position within a laboratory at the interface of virology and immunology. The researcher will have opportunities to present and publish their research. The Langlois lab offers a dynamic laboratory environment with a variety of research techniques, experimental approaches and research questions.
TYPICAL TASKS (These examples do not include all possible tasks in this work and do not limit the assignment of related tasks in any position of this class.) - 10% Perform molecular analyses including (PCR, quantitative PCR, DNA extraction, molecular cloning, CRISPR/Cas9, primer design). - 20% Make standard laboratory reagents (PBS and other buffers, LB media, Agar Plates, DMEM etc), keep the laboratory stocked and clean, and maintain all laboratory equipment. - 30% Supports scientists in the laboratory and conduct investigations or experiments in an assigned area to aid in the solution of a research problem (standard virology techniques, western blot, tissue culture work, learning and applying new techniques as needed etc), and preparing data for publication. - 10% Screening, weaning and general maintenance of mouse colonies. Handling and performing mouse experiments including anesthesia. - 20% Manage day to day laboratory operations (shipping and receiving, ordering supplies, inventory). -10% Duties as assigned
About the lab:
Influenza A virus (IAV) represents a major global health burden. The virus is able to escape seasonal immunity requiring yearly vaccination and the threat of novel pandemics loom. Therefore, continued understanding of the host-pathogen interactions and protective immune responses are critical for the development of therapeutic interventions and protective vaccines. We aim to address fundamental questions in virology and viral immunology that have been difficult to dissect using conventional approaches. We generate novel recombinant viruses, virus host model systems, and animal models to probe the antiviral responses.
We are also interested in how viruses evolve in the face of antiviral immune responses and how viruses make jumps into new species. To study this we use a newly developed model system to track viruses within both the reservoir and host, where we can perturb key components of the immune system in the host.
All required qualifications must be documented on application materials
REQUIRED QUALIFICATIONS - Bachelor's degree with a major in a biomedical science (Microbiology, Biochemistry, etc) or an equivalent combination of education and relevant research experience to equal four years.
PREFERRED QUALIFICATIONS - At least one year of research experience -Experience with cell culture and molecular biology techniques (cloning, PCR, nucleic acid extraction or - At least one year of experience in maintenance of mouse colonies/working with mice or - Experience with flow cytometry and/or fluorescence microscopy
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.