The Animal Technician Specialist will assist with the conduct of highly specialized and technically complex experiments using small animal models (rodents and rabbits) of infection with various bio-safety level 2 and 3 pathogens and providing technical support for the BSL-3 Labs. Studies will be carried out in Animal Biosafety Level 2 (ABSL-2) and Animal Biosafety Level 3 (ABSL-3) facilities and focus on infections via aerosol, intranasal, intraperitoneal, intravenous intradermal and subcutaneous routes; intraperitoneal, intramuscular, subcutaneous and intravenous injections of rodents and other small animals with therapeutics and/or anesthesia; necropsy to isolate the organs; evaluate tissue burdens; isolation of single cell suspension from infected tissue.
The Center for Discovery and Innovation (CDI), was established by Hackensack Meridian Health (HMH) as an academic basic and translational research enterprise to rapidly translate science innovation to the clinic to improve outcomes for patients with cancer, infectious diseases, autoimmune disease and other acute and chronic diseases. The CDI has grown rapidly since its origins in 2019, and now has 18 labs, 150 scientists and support personnel, who are supported by more than 85 grants and contracts. Areas of expertise include genomics, epigenetics, drug resistance, stem cell biology, drug discovery, diagnostics and biomarker development, and pharmacology.
Essential Generic Job Functions (List in order of importance):
Assist with performing various research and technical operations relative to ongoing projects to bacterial, fungal and viral pathogens (Evaluation of therapeutics, development of novel diagnostics and studies in pathogenesis and virulence).
Assist with preparation of BSL-2 and BSL-3 pathogen cultures.
Assist in analysis of host immune response using Flow cytometry and other immunological methods
Perform other laboratory analytical assays such as real time PCR, ELISA and western blots.
Set-up, maintain, sterilize, and decontaminate the devices for aerosol infection, homogenizer, and other equipment.
Autoclave waste materials and clean biosafety cabinets and equipment.
Understands and adheres to HMH CDI compliance standards.
Keeps abreast of all pertinent federal and state regulations, laws and policies as they presently exist and as they change or are modified.
Lifting and handling of laboratory animals and feed/equipment up to 50 pounds.
Bachelor’s degree in a relevant science or equivalent work experience.
Minimum of 2 years of experience in work with animal infection models under Biosafety level 3 containment.
Experience in infectious diseases.
Basic knowledge in Microbiology, Immunology, Molecular Biology and Biochemistry.
Good organization and record-keeping skills.
Excellent interpersonal and communication skills are critical.
All candidates must enroll and be given clearance by the Federal Bureau of Investigation (FBI) and Criminal Justice Information Services Division (CJIS) Security Risk Assessment.
Must retain clearance to work with HHS Tier 1 Select Agents and be enrolled in the Select Agent Program Personnel Reliability Program
The Hackensack Meridian Health Center for Discovery and Innovation (CDI) is an academic-based entrepreneurial center that rapidly harnesses innovations arising from a new renaissance in biomedical sciences to restore patient health. It is comprised of three distinct institutes with a shared mission, as follows:
The Institute for Cancer and Infectious Diseases (iCID) is dedicated to understanding fundamental biological insights of cancer cells and opportunistic pathogens (bacterial, viral and fungal) causing infection in immunocompromised patients, and to applying these insights to overcome these diseases through innovative strategies for detection, prevention, and therapeutic intervention.
The Institute for Multiple Myeloma and Lymphoma (iMML) is dedicated to expediting the development of breakthrough ideas relating to the treatment of multiple myeloma to their full expression in preclinical studies, clinical trials and approved interventions, ultimately offering life-saving care for patients.
The Institute for Restorative Health (iRH) will offer novel solutions to heal damaged tissues and organs, and provide hope to restore health for patients with conditions that today cannot be treated.