This is an exciting opportunity to join the Genomics Services Unit of the Wisconsin National Primate Research Center, part of a leading biomedical research program run by Dr. David O'Connor. The successful applicant will help develop, design, organize, and conduct research projects under the supervision of Dr. O'Connor and senior scientists in the lab. They will actively participate in a team studying genomic variability and immune system genetics of nonhuman primates, with an emphasis on genotyping major histocompatibility complex (MHC), killer immunoglobulin-like receptor (KIR), and Fc gamma receptor (FCGR) loci. More information on the Genomics Services Unit can be found at https://primate.wisc.edu/research-services/genomics-services/, and more about Dr. O'Connor's overall research program can be found at https://dho.pathology.wisc.edu/.
The successful candidate will be knowledgeable in biological science concepts, have some experience in writing scripts to automate workflows (experience with Python is preferred) for the generation and analysis of large DNA sequencing datasets, and be responsible for analyzing and communicating experimental results. Applicants will also collaborate with UW-Madison IT system administrators to orchestrate the lab's networking and computer processing of large datasets, establish connectivity to equipment, and ensure appropriate and robust data storage and management.
Assists with the analysis and interpretation of collected data and drafts reports to develop and communicate research findings.
40% Analyzes data and summarizes research results for a defined research area or study by utilizing established processes
15% Prepares reports and manuscripts and assists with the development and presentation of materials through various communication platforms
15% Maintains organization of research records and responds to data requests and inquiries
10% Serves as an initial point of contact for individuals and groups providing basic information about result analysis and methodologies, answers questions as needed
20% Liaise with stakeholders including but not limited to IT, WNPRC, funders, and lab members to generate, maintain, backup, and publicly disseminate raw and interpreted laboratory data.
Institutional Statement on Diversity:
Diversity is a source of strength, creativity, and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity, culture, background, experience, status, abilities, and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching, research, outreach, and diversity as inextricably linked goals.
The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background - people who as students, faculty, and staff serve Wisconsin and the world.
Required Bachelor's Degree in computer science, genetics, immunology, virology, microbiology or related field, with lab experience. Higher degrees will also be considered.
Incumbent must be able to understand complex concepts of genetics, immunology, molecular biology, and/or virology. The successful applicant is expected to perform literature reviews and assimilate new knowledge in topics pertaining to their research. The ability to multitask, learn new tasks, pay attention to detail, and organize many types of data from multiple projects accurately is essential for success in this role.
Experience analyzing deep sequencing DNA datasets from Illumina MiSeq and NovaSeq, PacBio Sequel II and/or Oxford Nanopore Technologies MinION and GridION platforms are strongly preferred. Experience with writing scripts to automate workflows (experience with Python is preferred) for the generation and analysis of large DNA sequencing datasets is preferred. The successful applicant will analyze large data sets, such as those generated from whole genome/whole exome sequencing, including genome-wide variant analysis and specialized reporting of genotypes in immunologically complex regions such as the MHC. Since the biology of the immunologically complex regions differs in important ways between humans and macaques, it is valuable for the successful candidate to have the biological background in genomics concepts (e.g., genes, alleles, haplotypes, genotypes, linkage) that are needed to correctly interpret genomics datasets.
It is anticipated this position requires work be performed in-person, onsite, at a designated campus work location.
Appointment Type, Duration:
Minimum $50,000 ANNUAL (12 months) Depending on Qualifications
The WNPRC is one of seven federally supported National Primate Research Centers and the only one in the Midwest. WNPRC's mission is to increase the understanding of basic primate biology and to improve human health and quality of life through research. To accomplish this, the WNPRC helps discover treatments, preventions and cures for human disease; generates new knowledge of primate biology, from the molecular and whole animal levels to the understanding of primate ecosystems; facilitates research progress by providing expertise, resources and training to scientists worldwide; and collects primate information and disseminates to the research community and to the public.
Based in the Office of the Vice Chancellor for Research and Graduate Education (OVCRGE) of the University of Wisconsin-Madison (UW-Madison), the WNPRC is committed to diversity both as an end in itself, but also as a valuable means for eliminating health disparities through research.
How to Apply:
Please click "Apply Now" to begin the application process. Please submit a cover letter and resume highlighting your experience as it relates to this position, referencing PVL 266595. You will also be required to provide three professional references, with phone numbers and email addresses.
Employment will require a criminal background check. It will also require you and your references to answer questions regarding sexual violence and sexual harassment.
The University of Wisconsin System will not reveal the identities of applicants who request confidentiality in writing, except that the identity of the successful candidate will be released. See Wis. Stat. sec. 19.36(7).
The University of Wisconsin–Madison has been a catalyst for the extraordinary since its founding in 1848. Our students, staff, and faculty partake in world-class education and conduct prolific research that solves real-world problems. Our guiding principle is the Wisconsin Idea, a commitment to outreach that creates a better future for our state, our nation, and the world. We value the contributions of each person and recognize that diversity is a source of strength, creativity, and innovation.