A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
The applicant will work closely with the PI and senior members of the lab for the design of experiments in the Department of Periodontics and Oral Medicine at the University of Michigan School of Dentistry applying cell culture and molecular biology skills. The candidate must be comfortable in working with animals.
The successful candidate will be primarily responsible for conducting research related to the molecular control of tumor dormancy of bone metastatic prostate cancer initiated by bone marrow stem cell niche using in vivo models. The candidate will also be working on research projects related to bone regeneration, periodontal disease progression, and wound healing responses by modulating the innate immune system.
In consultation with the PI, responsible for the design and execution of experiments.
Prepare research results for basic data analysis, publication and for grant submission.
Assist the PI in the writing of grant proposals and the acquisition of support from outside agencies.
General animal care, breeding of animals from different genetic backgrounds.
Assist with animal studies and surgeries for other lab members.
Tail biopsy, ear tagging, DNA isolation and PCR genotyping.
Tissue dissection, processing and staining.
Light microscopic examination of cell numbers and counting.
Tissue culture and cell proliferation, invasion and migration assays.
Cell purification from blood and marrow samples.
Compilation of experimental data, inventories and reports.
Some mentoring of students.
Responsible for lab organization, perform laboratory maintenance activities, including preparing general lab solutions, sterilizing lab equipment, ordering supplies, maintenance and documentation of lab safety for compliance, and data collection/management.
Bachelor's degree in Biology, Biochemistry & Biophysics, Cell/Cellular Biology, Genetics, Microbiology, Immunology, Biomedical Sciences, or Biomedical Engineering. Minimum of 1 year research experience working with in vivo animal models and excellent animal handling skills are required. Excellent organizational skills along with excellent communication skills. Excellent attention to details, excellent ability to multitask, and ability to maintain regular attendance in order to complete the responsibilities of the position.
Experience with flow cytometry or related research experience and publications would be helpful.
Some experience mentoring research personnel.
This is a one (1)-year term appointment with the possibility of renewal following the initial year contingent upon performance and funding. The salary range quoted for this position reflects 100% effort (40 hours per week).
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks will be performed in compliance with the Fair Credit Reporting Act.
MDentistry: advancing health through education, service, research and discovery.
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The University of Michigan is an equal opportunity/affirmative action employer.
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