The Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University (OHSU) has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. The development of this unique program in immunology and virology provides an important training opportunity for graduate students and postdoctoral fellows at OHSU. This is why an important part of our mission is the training of young scientists in newer academic disciplines emerging at the Vaccine and Gene Therapy Institute.
Function/Duties of Position
Uncontrolled inflammation generates significant morbidity and mortality in many diseases of infectious (e.g. HIV, Mtb) and non-infectious (e.g. inflammatory bowel disease) origin. By utilizing a variety of non-human primate models of human diseases, the Estes Laboratory works to elucidate determinants of local and systemic inflammation leading to tissue pathology, disease progression, and pathogen persistence, as well as test therapeutics to modulate the immune landscape, restore immune homeostasis, and reduce pathogen tissue reservoirs.
The Estes Lab is currently recruiting a highly self-motivated and energetic postdoctoral researcher to lead a project within the new multi-center Cascade IMPAc-TB consortium, an ambitious NIH contract designed to accelerate progress in tuberculosis vaccine development. In collaboration with the Gerner Lab in Seattle, this project is designed to provide a spatial framework, via advanced in situ hybridization and immunofluorescent techniques, that will complement and synergize with other consortium projects. Additionally, this individual will also lead and collaborate on other projects within the lab, including projects to understand HIV/SIV reservoir dynamics. Background in a relevant immunology lab is required. Direct experience working on TB, HIV/SIV, non-human primate models, multiplexed in situ hybridization and protein immunofluorescence, and/or multispectral imaging is highly desirable.
Please note that this position is at OHSU's West Campus (Beaverton). Submit a resume, cover letter, and at least three references to be considered for this position.
Required Qualifications
Ph.D. in immunology, microbiology, virology, or closely related field
Research experience with in vivo models of TB, HIV, SIV, non-human primates, advanced microscopy, multi-spectral imaging, or closely related areas.
Must be a team player, have excellent oral and written communication skills, willing to work with non-human primate and/or biohazardous samples, and comfortable using computers (Mac, PC), databases, and advanced software programs.
Preferred Qualifications
First-author publications involving the immunology or pathology of TB, HIV, SIV, non-human primates, advanced microscopy, or multi-spectral imaging.
Experience with animal research, especially non-human primates, image analysis experience, and Python programing.
All are welcome
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu. As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm
