DESCRIPTION

The Aguado iBiomaterials Lab is focused on developing biomaterials technologies for precision medicine applications. Under close technical supervision, the Staff Research Associate will assist the Principal Investigator, manage day-to-day laboratory operations, perform standard laboratory techniques, and maintain general laboratory tasks in a biomaterials laboratory.

Incumbent will be responsible for starting and maintaining mouse colonies, perform mouse surgeries, perform mouse euthanasia and dissection procedures, starting and expanding mammalian cell stocks, synthesizing polymer-based biomaterials, organize laboratory data on university/laboratory servers, writing and renewing animal (IACUC) and human institutional review board (IRB) protocols, serve as our laboratory safety officer, and complete routine laboratory duties (ordering/quoting equipment, organizing, maintenance, making solutions, writing standard operating procedures) and assist lab members with general laboratory techniques and basic molecular biology techniques (Western blots, quantitative PCR, immunofluorescence staining). Incumbent will also closely cooperate and provide direction for future postdoctoral fellows, graduate students, and undergraduate students.

Functions and Tasks:Research and Analysis:

A. Start and expand mammalian cell stocks: task involves harvesting cells from animal and/or human tissue samples, growing them in culture, and freezing cell stocks for future experiments.

B. Perform chemical syntheses: task involves chemically functionalizing polymer materials, performing quality control tests using nuclear magnetic resonance characterization, and storing material stocks for laboratory use.

C. Organize laboratory data: task involves oral and written communication with information technology staff to assist with lab server set up, experimental data analysis assistance as needed.

D. Write animal and human institutional review board (IRB) protocols: in consultation with the PI, the task involves writing, submitting, and renewing animal and human protocols as needed.

E. Maintain mouse colonies, order mice, perform mouse surgeries, perform mouse euthanasia and dissection procedures.

Laboratory Management:

A. Ensure lab safety protocols are followed, and assist with writing standard operation procedures, and protocols.

B. Perform basic laboratory maintenance and management in support of a laboratory.

C. Responsible for ordering laboratory supplies, servicing and maintaining all laboratory equipment.

D. Coordinate activities of laboratory assistants and student working on associated projects.

E. Assist and train others in general laboratory techniques and basic/repetitive molecular biology techniques.

F. Contribute to laboratory safety by monitoring safety, advising personnel about rules and regulations, maintaining safety supplies, checking fire extinguishers, and supervising procedures and records necessary for compliance with Environment, Health & Safety (EH&S) regulations.

Manuscript Writing:

Assist PI with writing and submitting manuscripts for publication, reading manuals for equipment, reading primary literature articles for improving laboratory techniques, etc.

QUALIFICATIONS

1. Bachelor's degree in bioengineering, biomedical engineering, or biology AND two (2) years of laboratory experience in biomaterials, cell/animal biology, chemistry; OR an equivalent combination of education and experience.

2. Previous laboratory experience including familiarity with basic microbiological and sterile techniques, and the ability to follow multi-step assays and procedures.

3. Previous experience working with animals for biomedical research (breeding, genotyping, etc).

4. Successful, positive interpersonal and oral and written communication skills using tact, diplomacy, discretion, and flexibility with diverse personalities and situations. Skill to interact effectively with faculty, academics, students, and staff including those of diverse ethnicity, culture, and foreign nationals.

5. Demonstrated ability to work with minimum supervision and to work closely and collaboratively with others including the ability to follow written and

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