Research Opportunities - Pediatrics Hematology Oncology
Washington University in St. Louis
Location: St. Louis, Missouri
Internal Number: JR73624
The laboratory of Dr. Melissa Mavers studies graft-versus-host disease (GVHD), an immune-mediated complication of stem cell transplantation. Through transcriptomic, proteomic, and functional analyses of immune regulatory cells, the Mavers Lab seeks to enhance understanding of the role of immunosuppressive cells in GVHD. Her laboratory has the goal of using a bench-to-bedside approach for developing a cellular therapy for GVHD, engineering viable approaches to prevention and cure.
Work in the lab involves the investigation of a type of innate lymphocyte, the invariant natural killer T cell, which is of interest due to its potential ability to suppress GVHD and promise as a therapeutic. Analyses include flow cytometry/fluorescence activated cell sorting, enzyme-linked immunosorbent assays, other bead-based and colorimetric assays, and RNA-sequencing; therefore, this position requires excellent laboratory record keeping skills and may include basic data analysis. Previous tissue culture/cell culture experience, or experience in at least one of the aforementioned assays, would be a plus. Additionally, due to the significance of mouse model experiments for the Mavers Lab, training in mouse colony maintenance and murine laboratory techniques and models will also be available. Please note that willingness to work with mice will be required, though prior experience is not necessary.Â
The Mavers lab strives to provide an environment of growth and support alongside its inclusive culture. We are focused on producing high quality science and are seeking a self-motivated individual capable of performing intricate experiments who is looking to grow and contribute in a highly collaborative environment. Further technical training opportunities range from basic to advanced microbiology and analysis techniques including, but not limited to, cloning, PCR, and viral transduction, as well as the assays listed in detail above. Dr. Mavers also provides career mentorship, opportunities for authorship to all contributing individuals, potential opportunities for independent work, and an overall value towards growing your own scientific acumen and professional repertoire.Â
Works in laboratory environment with potential exposure to biological, chemical and radioactive hazards.Â Must be physically able to wear protective equipment and to provide standard care to research animals.
Base pay is commensurate with experience.
Previous tissue culture/cell culture experience, in addition to experience in at least one of the assays below, would be a plus:
flow cytometry/fluorescence activated cell sorting, enzyme-linked immunosorbent assays, other bead-based and colorimetric assays, and RNA-sequencingâ‹
Ability to maintain complete and organized records/reports.
Working knowledge of computer software and general lab equipment.
Bachelorâ™s degree with one year of experience in a laboratory setting or equivalent combination of education and experience equaling four years required.
Willingness to work with mice.
If you are unable to use our online application system and would like an accommodation, please emailÂ CandidateQuestions@wustl.eduÂ or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the Universityâ™s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.