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Researcher - Comprehensive Cancer Center
About the lab: The Blair lab focuses on novel immunotherapeutics for pancreatic adenocarcinoma with a particular interest in innate immunity, STING signaling, synergistic effects of radiation and the plasticity of tumor stroma. We focus on rational combinations of agents that target the tumor microenvironment to increase effector immune cell infiltration and tumor-eradicating function. The lab focuses on preclinical mouse models, but supplements this with in vitro cell work to understand changes in signaling and expression, as well as analysis of treated human tissue from clinical trials leveraging our robust tissue biobank. Our current projects center around leveraging a novel nanoparticle agent that targets the STING pathway to up regulate an otherwise dampened immune response


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